Protonation‐Driven Membrane Insertion of a pH‐Low Insertion Peptide
نویسندگان
چکیده
منابع مشابه
Interfacial folding and membrane insertion of a designed helical peptide.
Nonconstitutive membrane-active proteins, such as diphtheria toxin, must refold on membrane interfaces in the course of membrane penetration. A useful step in deciphering this process is to understand quantitatively the energetics of interface-mediated insertion of model transmembrane helices. A difficulty is that peptides that are sufficiently hydrophobic to span a lipid bilayer have a strong ...
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ژورنال
عنوان ژورنال: Angewandte Chemie International Edition
سال: 2016
ISSN: 1433-7851,1521-3773
DOI: 10.1002/anie.201605203